Lilly drug chosen for Alzheimer's prevention study


Researchers have chosen an experimental drug by Eli Lilly & Co. for a large federally funded study testing whether it's possible to prevent Alzheimer's disease in older people at high risk of developing it.


The drug, called solanezumab (sol-ah-NAYZ-uh-mab), is designed to bind to and help clear the sticky deposits that clog patients' brains.


Earlier studies found it did not help people with moderate to severe Alzheimer's but it showed some promise against milder disease. Researchers think it might work better if given before symptoms start.


"The hope is we can catch people before they decline," which can come 10 years or more after plaques first show up in the brain, said Dr. Reisa Sperling, director of the Alzheimer's center at Brigham and Women's Hospital in Boston.


She will help lead the new study, which will involve 1,000 people ages 70 to 85 whose brain scans show plaque buildup but who do not yet have any symptoms of dementia. They will get monthly infusions of solanezumab or a dummy drug for three years. The main goal will be slowing the rate of cognitive decline. The study will be done at 50 sites in the U.S. and possibly more in Canada, Australia and Europe, Sperling said.


In October, researchers said combined results from two studies of solanezumab suggested it might modestly slow mental decline, especially in patients with mild disease. Taken separately, the studies missed their main goals of significantly slowing the mind-robbing disease or improving activities of daily living.


Those results were not considered good enough to win the drug approval. So in December, Lilly said it would start another large study of it this year to try to confirm the hopeful results seen patients with mild disease. That is separate from the federal study Sperling will head.


About 35 million people worldwide have dementia, and Alzheimer's is the most common type. In the U.S., about 5 million have Alzheimer's. Current medicines such as Aricept and Namenda just temporarily ease symptoms. There is no known cure.


___


Online:


Alzheimer's info: http://www.alzheimers.gov


Alzheimer's Association: http://www.alz.org


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Follow Marilynn Marchione's coverage at http://twitter.com/MMarchioneAP


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Wall Street Week Ahead: Earnings, money flows to push stocks higher

NEW YORK (Reuters) - With earnings momentum on the rise, the S&P 500 seems to have few hurdles ahead as it continues to power higher, its all-time high a not-so-distant goal.


The U.S. equity benchmark closed the week at a fresh five-year high on strong housing and labor market data and a string of earnings that beat lowered expectations.


Sector indexes in transportation <.djt>, banks <.bkx> and housing <.hgx> this week hit historic or multiyear highs as well.


Michael Yoshikami, chief executive at Destination Wealth Management in Walnut Creek, California, said the key earnings to watch for next week will come from cyclical companies. United Technologies reports on Wednesday while Honeywell is due to report Friday.


"Those kind of numbers will tell you the trajectory the economy is taking," Yoshikami said.


Major technology companies also report next week, but the bar for the sector has been lowered even further.


Chipmakers like Advanced Micro Devices , which is due Tuesday, are expected to underperform as PC sales shrink. AMD shares fell more than 10 percent Friday after disappointing results from its larger competitor, Intel . Still, a chipmaker sector index <.sox> posted its highest weekly close since last April.


Following a recent underperformance, an upside surprise from Apple on Wednesday could trigger a return to the stock from many investors who had abandoned ship.


Other major companies reporting next week include Google , IBM , Johnson & Johnson and DuPont on Tuesday, Microsoft and 3M on Thursday and Procter & Gamble on Friday.


CASH POURING IN, HOUSING DATA COULD HELP


Perhaps the strongest support for equities will come from the flow of cash from fixed income funds to stocks.


The recent piling into stock funds -- $11.3 billion in the past two weeks, the most since 2000 -- indicates a riskier approach to investing from retail investors looking for yield.


"From a yield perspective, a lot of stocks still yield a great deal of money and so it is very easy to see why money is pouring into the stock market," said Stephen Massocca, managing director at Wedbush Morgan in San Francisco.


"You are just not going to see people put a lot of money to work in a 10-year Treasury that yields 1.8 percent."


Housing stocks <.hgx>, already at a 5-1/2 year high, could get a further bump next week as investors eye data expected to support the market's perception that housing is the sluggish U.S. economy's bright spot.


Home resales are expected to have risen 0.6 percent in December, data is expected to show on Tuesday. Pending home sales contracts, which lead actual sales by a month or two, hit a 2-1/2 year high in November.


The new home sales report on Friday is expected to show a 2.1 percent increase.


The federal debt ceiling negotiations, a nagging worry for investors, seemed to be stuck on the back burner after House Republicans signaled they might support a short-term extension.


Equity markets, which tumbled in 2011 after the last round of talks pushed the United States close to a default, seem not to care much this time around.


The CBOE volatility index <.vix>, a gauge of market anxiety, closed Friday at its lowest since April 2007.


"I think the market is getting somewhat desensitized from political drama given, this seems to be happening over and over," said Destination Wealth Management's Yoshikami.


"It's something to keep in mind, but I don't think it's what you want to base your investing decisions on."


(Reporting by Rodrigo Campos, additional reporting by Chuck Mikolajczak and Caroline Valetkevitch; Editing by Kenneth Barry)



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Hostages still held after Sahara assault


ALGIERS (Reuters) - At least 22 foreign hostages remained unaccounted for on Friday after Algerian forces stormed a desert gas complex to free hundreds of captives taken by Islamist gunmen, an operation in which dozens of the hostages were killed.


With Western leaders clamoring for details of the assault they said Algeria had launched on Thursday without consulting them, a local source said the gas base was still surrounded by Algerian special forces and some hostages remained inside.


Thirty hostages, including several Westerners, were killed during the storming on Thursday, the source said, along with at least 11 of their captors, who said they had taken the site as retaliation for French intervention against Islamists in neighboring Mali.


Fourteen Japanese were among those still unaccounted for by the early hours of Friday, their Japanese employer said, while Norwegian energy company Statoil, which runs the Tigantourine gas field with Britain's BP and Algeria's national oil company, said eight Norwegian employees were still missing.


An Irish engineer who survived said he saw four jeeps full of hostages blown up by Algerian troops whose commanders said they moved in about 30 hours after the siege began because the gunmen had demanded to be allowed to take their captives abroad.


The crisis posed a serious dilemma for Paris and its allies as French troops attacked the hostage-takers' al Qaeda allies in Mali. It also left question marks over the ability of OPEC-member Algeria to protect vital energy resources and strained its relations with Western powers.


Two Japanese, two Britons and a French national were among at least seven foreigners killed, the source told Reuters. Eight dead hostages were Algerian. The nationalities of the rest, as well as of perhaps dozens more who escaped, were unclear. Some 600 local Algerian workers, less well guarded, survived.


A diplomatic source said Britain had not received any information to suggest the hostage situation had ended. "The situation is still really fluid on the ground. We have no information from the Algerian authorities that it's over."


Japan's Prime Minister Shinzo Abe has cancelled part of his trip in Southeast Asia, his first overseas trip since taking office, and will fly home early due to the hostage crisis, Japan's senior government spokesman said on Friday.


"The action of Algerian forces was regrettable," said Japan's Chief Cabinet Secretary Yoshihide Suga, adding Tokyo had not been informed of the operation in advance.


Americans, Romanians and an Austrian have also been mentioned by their governments as having been captured by the militants, who call themselves the "Battalion of Blood" and have demanded France end its week-old offensive in Mali.


Underlining the view of African and Western leaders that they face a multinational Islamist insurgency across the Sahara - a conflict that prompted France to send hundreds of troops to Mali last week - the official source said only two of the 11 dead militants were Algerian, including the squad's leader.


The bodies of three Egyptians, two Tunisians, two Libyans, a Malian and a Frenchman - all assumed to have been hostage-takers - were found, the security source said.


The group had claimed to have dozens of guerrillas on site and it was unclear whether any militants had managed to escape.


The overall commander, Algerian officials said, was Mokhtar Belmokhtar, a veteran of Afghanistan in the 1980s and Algeria's bloody civil war of the 1990s. He appears not to have been present and has now risen in stature among a host of Saharan Islamists, flush with arms and fighters from chaotic Libya, whom Western powers fear could spread violence far beyond the desert.


"NO TO BLACKMAIL"


Algeria's government made clear it remains implacably at odds with Islamist guerrillas who remain at large in the south, years after the civil war in which some 200,000 people died. Communication Minister Mohamed Said repeated their refusal ever to negotiate with hostage-takers.


"We say that in the face of terrorism, yesterday as today as tomorrow, there will be no negotiation, no blackmail, no respite in the struggle against terrorism," he told APS news agency.


British Prime Minister David Cameron, who warned people to prepare for bad news and who cancelled a major policy speech on Friday to deal with the situation, said through a spokesman that he would have liked Algeria to have consulted before the raid.


A Briton and an Algerian were also killed on Wednesday.


U.S. officials had no clear information on the fate of Americans, though a U.S. military drone had flown over the area. Washington, like its European allies, has endorsed France's move to protect the Malian capital by mounting air strikes last week and now sending 1,400 ground troops to attack Islamist rebels.


A U.S. official said on Thursday it would provide transport aircraft to help France with a mission whose vital importance, President Francois Hollande said, was demonstrated by the attack in Algeria. Some fear, however, that going on the offensive in the remote region could provoke more bloodshed closer to home.


The apparent ease with which the fighters swooped in from the dunes to take control of an important energy facility, which produces some 10 percent of the natural gas on which Algeria depends for its export income, has raised questions over the value of security measures that are outwardly draconian.


(Additional reporting by Ali Abdelatti in Cairo, Eamonn Mallie in Belfast, Gwladys Fouche in Oslo, Mohammed Abbas in London and Padraic Halpin and Conor Humprhies in Dublin; writing by Alastair Macdonald and Philippa Fletcher; editing by Peter Millership, Michael Perry and Will Waterman)



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Inspiring Singers Outshine American Idol's Feuding Judges






American Idol










01/17/2013 at 11:00 PM EST







From left: Randy Jackson, Mariah Carey, Ryan Seacrest, Nicki Minaj and Keith Urban


George Holz/FOX


The second episode of American Idol delivered more drama, but a handful of singers managed to eclipse the ongoing feud between new judges Mariah Carey and Nicki Minaj. And that's no easy task considering one of the battling divas is wearing a blonde and pink wig.

The night's most memorable contestant was Lazaro Arbos. As he entered the audition room, one thing became immediately clear: the 21-year-old from Naples, Fla., had a severe stutter. Arbos, who emigrated from Cuba when he was 10, told viewers that he had few friends growing up due to his speech impediment.

But something magical happened when he began to sing. His stutter vanished and he gave a moving performance of "Bridge Over Troubled Water." As the judges unanimously put him through to Hollywood, Arbos dissolved into tears.

Equally inspiring was Mariah Pulice, a 19-year-old restaurant hostess from Darien, Ind. The last two years have been difficult for Pulice, who told judges she was recovering from anorexia. "If there was no music," she said, "I would not be alive." After singing the Beatles' "Let it Be," the judges were unanimous in their praise. "I really, really, really felt that song coming from you," said Minaj.

Carey agreed: "You touched me," she said. "I know what it's like to have to sing through tears. I'm proud of you."

But it wasn't all drama and emotion. Minaj started a baffling trend of asking handsome singers if they had a girlfriend. (She also managed to charm the shirts off of a couple of them, although you get the feeling they were happy to show their abs on national TV.) "You have a hole in your pants," she told one contestant. "Why are you looking?" he shot back.

And poor Keith Urban. Sitting between Minaj and Carey, he found himself in the crossfire. "I feel like a scratching post," he said at one point, before repeatedly banging his head on the table.

The judges found a lot of talent in Chicago. All told, 46 contestants were put through to Hollywood. The competition will head to Charlotte, N.C., next Wednesday.

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Chinese, U.S. data push global shares to twenty-month high

LONDON (Reuters) - World shares hit a 20-month high on Friday as encouraging data from the United States and China boosted prospects for the global economy, while the yen hit new lows ahead of next week's Bank of Japan meeting.


China's economy grew at a slightly faster-than-expected 7.9 percent in the fourth quarter of 2012, the latest sign it is pulling out of a post-global financial crisis slowdown that produced its weakest year of economic growth since 1999.


The positive news came on top of strong U.S. labor and housing market reports on Thursday, providing fresh impetus to a recent strong and broad financial market rally.


MSCI's index of leading world shares <.miwd00000pus> was at it highest level since May 2011 at 551.90 points as trading got underway in Europe and after Tokyo and Hong Kong stock markets surged and the S&P 500 in New York hit a five-year high.


"We've got good numbers out of China, we had some good numbers out of U.S. yesterday ... The general sentiment is pretty good," said Neil Marsh, strategist at Newedge.


"There will probably be some phases of consolidation as we go forward, but the markets remain pretty resilient. More people are putting their cash to work now in riskier assets like equities, and there is no sign of that stopping at the minute."


European stocks opened higher, with London's FTSE 100 <.ftse>, Paris's CAC-40 <.fchi> and Frankfurt's DAX <.gdaxi> up between 0.2 and 0.3 percent <.l><.eu><.n>. The region's data highlight of the day comes from British retail figures.


Industrial commodities jumped, leaving platinum and palladium near multi-month highs hit on Thursday, while oil prices edged up, with U.S. crude up 0.1 percent at $95.61 a barrel and Brent futures adding 0.2 percent to $111.27.


YEN SLIDE RESUMES


The strong U.S. data and mounting expectations for more aggressive easing by the Bank of Japan (BOJ) next week lifted the dollar to its highest since June 2010 of 90.21 yen, and the euro to its peak since May 2011 of 120.73 yen.


The single currency was steady against the dollar at $1.3378.


Expectations that the new Japanese government will pursue massive fiscal spending and push for more aggressive BOJ easing to drive Japan out of years of deflation and economic slump have spurred heavy yen selling since November.


Sources told Reuters the BOJ will at its January 21-22 meeting consider removing the 0.1 percent floor on short-term interest rates and commit to open-ended asset buying until the 2 percent inflation target is reached.


In bond markets, German two-year government bond yields rose 0.25 percent to near their highest in nearly 10 months, with traders citing growing concerns in money markets over early bank repayments of three-year European Central Bank loans.


Banks can start making repayments on January 30, and the ECB will publish how much will be repaid then on January 25. A larger-than-expected repayment of around 400 billion euros would effectively tighten conditions and push up interbank rates.


(Reporting by Marc Jones; Editing by Will Waterman)



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Sahara hostage siege turns Mali war global


ALGIERS/BAMAKO (Reuters) - Islamist gunmen holding dozens of Western hostages and scores of Algerians at a gas plant deep in the Sahara desert let some them speak to the media on Thursday to warn that they would be blown up if the site is stormed.


Governments around the globe were holding emergency meetings to respond to one of the biggest international hostage crises in decades, which sharply raises the stakes over a week-old French campaign against al Qaeda-linked fighters in neighboring Mali.


A group calling itself the "Battalion of Blood" says it seized 41 foreigners, including Americans, Japanese and Europeans, after storming a natural gas pumping station and employee barracks in Algeria before dawn on Wednesday.


The attackers have demanded an end to the French military campaign in Mali, where hundreds of French paratroops and marines are launching a ground offensive against rebels in a campaign that began a week ago with air strikes.


Algerian troops have the site surrounded, deep in the Sahara desert. An unidentified hostage who spoke to France 24 television said prisoners were being forced to wear explosive belts. Their captors were heavily armed and had threatened to blow up the base if the Algerian army tried to storm it.


"They attacked the two sites at the same time. They went inside, and once it was daylight they gathered everyone together," the man, who sounded calm, said in the only part of the phone call the French broadcaster aired.


Another hostage, identified as British, spoke to Al Jazeera television and called on the Algerian army to withdraw from the area to avoid casualties.


"We are receiving care and good treatment from the kidnappers. The (Algerian) army did not withdraw and they are firing at the camp," the man said.


"There are around 150 Algerian hostages. We say to everybody that negotiations is a sign of strength and will spare many any loss of life," he said, adding that there were about 150 Algerian hostages in custody.


Another hostage, identified as Irish, told the Qatar-based channel: "The situation is deteriorating. We have contacted the embassies and we call the Algerian army to withdraw ... We are worried because of the continuation of the firing. Among the hostages are French, American, Japanese, British, Norwegian and Irish."


In what it said was a phone interview with one of the hostage takers, the Mauritanian news agency ANI said Algerian security forces had tried to approach the facility at dawn.


"We will kill all the hostages if the Algerian army try to storm the area," it quoted the hostage taker as saying. Algeria has not commented on reports its troops tried to approach.


Algerian Interior Minister Daho Ould Kablia said the raid was led by Mokhtar Belmokhtar, a veteran Islamist guerrilla fighter who fought Soviet forces in Afghanistan in the 1980s and had recently set up his own group in the Sahara after falling out with other local al Qaeda leaders.


A holy warrior-cum-smuggler dubbed "The Uncatchable" by French intelligence and "Mister Marlboro" by some locals for his illicit cigarette-running business, Belmokhtar's links to those who seized towns across northern Mali last year are unclear.


NUMBERS UNCONFIRMED


The precise number and nationalities of foreign hostages could not be confirmed, with countries perhaps reluctant to release information that could be useful to the captors.


British Foreign Secretary William Hague confirmed one Briton had been killed and "a number" of other British citizens were being held. Algerian media said an Algerian was killed in the assault. Another local report said a Frenchman had died.


The militants said seven Americans were among their hostages - a figure U.S. officials said they could not confirm. Norwegian oil company Statoil said nine of its Norwegian staff and three Algerian employees were captive. Japanese media said five workers from Japanese engineering firm JGC Corp. were held. France has not confirmed whether any French citizens were held.


"This is a dangerous and rapidly developing situation," Britain's Hague told reporters in Sydney. "The safety of those involved and their co-workers is our absolute priority, and we will work around the clock to resolve this crisis."


U.S. Defense Secretary Leon Panetta said: "I want to assure the American people that the United States will take all necessary and proper steps that are required to deal with this situation."


Japan's Prime Minister Shinzo Abe, in Vietnam on the first leg of a Southeast Asian tour, told reporters that "Japan will never tolerate such an act", according to the Jiji news agency. His government held an emergency meeting and said it was working with other countries to free Japanese citizens.


One thing is clear: as a headline-grabbing counterpunch to this week's French buildup in Mali, it presents French President Francois Hollande with stark choices.


France's ambassador to Mali, Christian Rouyer, said the attack in Algeria demonstrated that the French were right on the need to intervene in Mali.


"We have the flagrant proof that this problem goes beyond just the north of Mali," Rouyer told France Inter radio. "Northern Mali is at heart of the problem, of course, but the dimension is really national and international, which gives even more justification to the French intervention."


Hollande has received backing from Western and African allies who fear that al Qaeda, flush with men and arms from the defeated forces of Libya's Muammar Gaddafi, is building a desert haven in Mali, a poor country that was helpless to combat fighters who seized its northern cities last year.


The Algerian government has ruled out negotiating with the hostage takers and the United States and other Western governments condemned the attack on a facility that produces 10 percent of Algeria's gas, much of which is pumped to Europe.


The militants, communicating through established contacts with media in neighboring Mauritania, said they had dozens of men armed with mortars and anti-aircraft missiles at the base and had rigged it with explosives.


They said they had repelled a raid by Algerian forces after dark on Wednesday. There was no government comment on that. Algerian officials said earlier about 20 gunmen were involved.


GOVERNMENTS HELD RESPONSIBLE


"We hold the Algerian government and the French government and the countries of the hostages fully responsible if our demands are not met, and it is up to them to stop the brutal aggression against our people in Mali," read one statement carried by Mauritanian media.


They condemned Algeria's secularist government for letting French warplanes fly over its territory to Mali. They also accused Algeria of shutting its border to Malian refugees.


Regis Arnoux, head of CIS, a French catering firm operating at the site, told BFM television he had been in touch with a manager of some 150 Algerian workers there. Local staff were being prevented from leaving but were otherwise free to move around inside and keep on working.


"The Westerners are kept in a separate wing of the base," Arnoux said. "They are tied up and are being filmed. Electricity is cut off, and mobile phones have no charge.


"Direct action seems very difficult ... Algerian officials have told the French authorities as well as BP that they have the situation under control and do not need their assistance."


Norway's Statoil operates the gas field in a joint venture with Britain's BP and the Algerian state company Sonatrach.


"Our total focus is on fixing this situation and returning our colleagues home," Statoil CEO Helge Lund told a news conference in Stavanger, western Norway. "Family, friends and colleagues are waiting for news from them."


Lund will travel later Thursday to Bergen, western Norway, to a crisis centre set up in a hotel by the company where some relatives of the hostages are gathering.


Japan's JGC Corp. said in a statement it was cooperating with the government but would not comment the number of its employees kidnapped.


In Mali, France said on Wednesday its forces were about to launch a ground assault on the rebels they began targeting from the air last week. Residents said a column of some 30 French Sagaie armoured vehicles set off toward rebel positions from the town of Niono, 300 km (190 miles) from the capital, Bamako.


Many inhabitants of northern Mali have welcomed the French attacks, although some also fear being caught in the cross-fire. The Mali rebels who seized Timbuktu and other oasis towns in northern Mali last year had imposed Islamic law, including public amputations and beheadings, that angered many locals.


"There is a great hope," one man said from Timbuktu, where he said Islamist fighters were trying to blend into civilian neighborhoods. "We hope that the city will be freed soon."


The rebels include fighters from al Qaeda's mainly Algerian-based North African wing AQIM as well as home-grown Malian groups Ansar Dine and MUJWA. Islamists have warned Hollande that he has "opened the gates of hell" for all French citizens.


The United Nations has authorized an African force to fight the rebels, and about 2,000 troops from Nigeria, Chad, Niger and other states are expected soon.


(Additional reporting by Pascal Fletcher and Andrew Callus in London, Balazs Koranyi in Oslo, Laurent Prieur in Nouakchott, Daniel Flynn in Dakar, John Irish, Catherine Bremer, Marine Pennetier, and Nick Vinocur in Paris, David Alexander in Rome, Andrew Quinn in Washington, Jane Wardell in Sydney, Omar Fahmy in Cairo, Mirna Sleiman in Dubai and Kaori Kaneko in Tokyo; Writing by Peter Graff and Alastair Macdonald)



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You Can Use Facebook for Free Cellphone Calls Now






Wait, what?


RELATED: Facebook’s Faster iPhone App Isn’t Fast Enough






Yes, theoretically you can kis those talk-time minutes from your cellphone data plan goodbye — as long as you’re content to have all your voice conversation with other Facebook users over data or Wi-Fi by way of your Messenger app. It’s called Voice Over Internet Protocol talking, and it’s the same thing that was supposed to help Skype take over the world last decade, and it might end up being a lot more useful to the savvy consumer’s pocketbook than the Graph Search, which Mark Zuckerberg called the “third pillar” of Facebook yesterday.


RELATED: Everything There Is to Know About That Facebook Phone


To make a call, all Facebook users have to do is tap the little “i” at the top right corner of the revamped app, which leads to the screen pictured above at right. As long as the other caller has the Messenger app, U.S. users can now tap Free Call, and, well, it’s just like making a phone call, really — except that instead of ringing, a push notification pops up: “You have a call from Carly.” (Seriously! We just tried it! It was free!)


RELATED: What Can Apple’s Acquisition of Chomp Mean?


Of course, this isn’t a Facebook-branded piece of hardware, or even the full-scale cellphone OS many have been drooling over as the social network figures out its mobile future. But this software could replace the traditional way we make calls. As we’ve explained before, Facebook has a lot of things going for it in taking VoIP calls to the masses in the way the Skype never really could: Messenger’s got all the right contacts, it costs almost nothing, and it even works in areas with terrible reception. Not to mention it works over data plans for everyone and not just people with compatible phones — Apple’s FaceTime feature only works on the iPhone 4S or 5, even if it’s more available now. Still, Facebook doesn’t have video chat for Messenger. But, hey, one world dominating step at a time, right?


Social Media News Headlines – Yahoo! News





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American Idol's New Judges Make Their Debut






American Idol










01/16/2013 at 11:00 PM EST







From left: Randy Jackson, Mariah Carey, Ryan Seacrest, Nicki Minaj and Keith Urban


Michael Becker/FOX.


American Idol is back!

Season 12 premiered Wednesday night with the first auditions in New York City. And fans hoping to get a taste of drama from new judges Mariah Carey and Nicki Minaj were not disappointed.

"Right away we knew it was going to be an interesting couple of days," host Ryan Seacrest said at the start of the two-hour episode.

And he was right. (Spoilers ahead!) While fellow newbie Keith Urban and veteran judge Randy Jackson were all about the business of finding talented singers, there was immediate tension between Carey and Minaj, who wore a drum major's hat to her first day on the job.

"We can have accessories?" Carey said disapprovingly after taking her seat at the panel. "I didn't know that was allowed."

"Why did you have to reference my hat?" Minaj responded.

Later, when Carey boasted about her holiday hit, "All I Want for Christmas," Minaj clenched her fists, gritted her teeth and used the b-word. Carey's response? "I rebuke it," she said.

The two women talked over each other at times, rolled eyes and seemed to annoy one another. More than once Carey said "Nicki" like an frustrated mother calls her child out for misbehaving. And Minaj pushed Carey's buttons by talking in a British accent.

But as the two formerly feuding judges have said in recent interviews, the show should be about the hopeful contestants – and there were a handful of talented singers who earned golden tickets to Hollywood:

• Tenna Torres, who attended Camp Mariah and had previously sung for the singer, impressed the panel with her version of "You've Got a Friend," and made her idol very proud.

• Christina "Isabelle," who told a story of losing weight and finding confidence, had Minaj saying, "OMG! OMG!" with her version of "Summertime."

• Frankie Ford, who sings for change on the New York City subway system, stumbled at first but delivered a soulful version of the Eurythmics' "Sweet Dreams." "I like your big voice," Urban said. "There's a lot of musicality in the tone."

Added Carey: "You have an inner glow, which is always beautiful to see."

• Despite hearing loss in both ears, Angela Miller, who sang "Mama Knows Best" by Jessie J, was "definitely one of the best," according to Jackson.

• And Ashlee Feliciano thrilled the female judges with her version of Corinne Bailey Rae's "Put Your Records On." "So pretty," Minaj said. "I want to come to your show ... I'm so inspired by you."

"The potential is great. It was beautiful," Carey said. "You should be really proud of yourself."

At the end of the first two days of auditions, the re-invented Idol panel had done its job: the judges praised the talented singers and handed out 41 tickets to Hollywood; they sent home the kooky contestants (often sweetly) and offered constructive criticism and an invitation to come back next year to the ones still on their way to greatness.

"We gel well in a weird crazy way," Minaj said at the end of the show. Carey said, "I agree."

We'll see how long that lasts! Auditions continue Thursday (8 p.m. ET) on Fox.

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Large study confirms flu vaccine safe in pregnancy


NEW YORK (AP) — A large study offers reassuring news for pregnant women: It's safe to get a flu shot.


The research found no evidence that the vaccine increases the risk of losing a fetus, and may prevent some deaths. Getting the flu while pregnant makes fetal death more likely, the Norwegian research showed.


The flu vaccine has long been considered safe for pregnant women and their fetus. U.S. health officials began recommending flu shots for them more than five decades ago, following a higher death rate in pregnant women during a flu pandemic in the late 1950s.


But the study is perhaps the largest look at the safety and value of flu vaccination during pregnancy, experts say.


"This is the kind of information we need to provide our patients when discussing that flu vaccine is important for everyone, particularly for pregnant women," said Dr. Geeta Swamy, a researcher who studies vaccines and pregnant women at Duke University Medical Center.


The study was released by the New England Journal of Medicine on Wednesday as the United States and Europe suffer through an early and intense flu season. A U.S. obstetricians group this week reminded members that it's not too late for their pregnant patients to get vaccinated.


The new study was led by the Norwegian Institute of Public Health. It tracked pregnancies in Norway in 2009 and 2010 during an international epidemic of a new swine flu strain.


Before 2009, pregnant women in Norway were not routinely advised to get flu shots. But during the pandemic, vaccinations against the new strain were recommended for those in their second or third trimester.


The study focused on more than 113,000 pregnancies. Of those, 492 ended in the death of the fetus. The researchers calculated that the risk of fetal death was nearly twice as high for women who weren't vaccinated as it was in vaccinated mothers.


U.S. flu vaccination rates for pregnant women grew in the wake of the 2009 swine flu pandemic, from less than 15 percent to about 50 percent. But health officials say those rates need to be higher to protect newborns as well. Infants can't be vaccinated until 6 months, but studies have shown they pick up some protection if their mothers got the annual shot, experts say.


Because some drugs and vaccines can be harmful to a fetus, there is a long-standing concern about giving any medicine to a pregnant woman, experts acknowledged. But this study should ease any worries about the flu shot, said Dr. Denise Jamieson of the Centers for Disease Control and Prevention.


"The vaccine is safe," she said.


___


Online:


Medical journal: http://www.nejm.org


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Futures signal mixed Wall Street open

LONDON (Reuters) - U.S. stock futures pointed to a mixed open on Wall Street on Thursday, with futures for the S&P 500 rising 0.1 percent, Dow Jones futures down 0.2 percent and Nasdaq 100 futures falling 0.1 percent.


Airlines scrambled on Thursday to rearrange flights as Europe, Japan and India joined the United States in grounding Boeing Co's 787 Dreamliner passenger jets while battery-related problems are investigated.


Earnings reports from major U.S. companies such as Citigroup , Intel , Bank of America and BlackRock , due later in the day, will be scrutinized for hints about the market's near-term direction.


First-time claims for jobless benefits for the week ended January 12 are due at 1330 GMT. Economists forecast a total of 365,000 new filings, compared with 371,000 in the previous week.


The Commerce Department releases housing starts and permits for December at 1330 GMT. Economists in a Reuters survey forecast a total of 903,000 permits in December, compared with 900,000 in the previous month.


Top executives at Goldman Sachs have been considering deep cuts to staffing levels and pay for at least two years, but feared too many layoffs would leave the firm unprepared for an eventual pickup in business, people familiar with the bank said.


Shares in Dutch telecoms company KPN rose more than 4 percent on Thursday after a report that U.S. peer AT&T is looking at an acquisition in Europe, including KPN and UK carrier Everything Everywhere.


AT&T is considering buying a telecoms company in Europe to offset growth constraints in its home market, the Wall Street Journal reported, citing unnamed people familiar with the company's thinking.


Taiwan Semiconductor Manufacturing Co Ltd reported a 32 percent rise in fourth-quarter profit as its cutting-edge technology keeps it ahead of rivals in the mobile gadget boom.


Philadelphia Federal Reserve Bank releases its January business activity survey at 1500 GMT. Economists forecast a reading of 5.8, versus 4.6 in December.


The pan-European FTSEurofirst 300 index <.fteu3> was flat in morning trading on Thursday.


The S&P 500 ended nearly flat on Wednesday as solid earnings from two major banks and a bounceback in Apple shares offset concerns about a lower forecast for global growth in 2013.


The Dow Jones industrial average <.dji> was down 23.66 points, or 0.17 percent, at 13,511.23 on Wednesday. The Standard & Poor's 500 Index <.spx> was up 0.29 points, or 0.02 percent, at 1,472.63. The Nasdaq Composite Index <.ixic> was up 6.77 points, or 0.22 percent, at 3,117.54.


(Reporting by Atul Prakash; Editing by Catherine Evans)



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